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Figure 1: (a) Cytology smear— sheets of malignant ductal cells on abundant necrotic background (H and E, ×100) (b) Pleomorphic cells having an ample amount of eosinophilic cytoplasm (H and E, ×400) (c) Histopathology microphotograph— large ducts with comedonecrosis and cribriform pattern (H and E, ×100) (d) Ducts with irregular contours surrounded by periductal stromal reaction and lymphocytic infiltrate (H and E, ×100) (e) Immunohistochemistry— p63— highlighting myoepithelial layer outlining the in situ component (H and E, ×100) (f) CK7— Strong and diffuse positivity in the in situ and invasive components (H and E, ×100) |
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