Journal of Cytology

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 38  |  Issue : 3  |  Page : 120--126

Role of Endobronchial ultrasound guided transbronchial needle aspiration with cellblocks in diagnosis and subtyping of intrathoracic lesions: Two year experience from a tertiary care center


Vikrant Verma1, Ajmal Khan2, Ram Nawal Rao1, Alok Nath2, Zia Hashim2 
1 Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
2 Department of Pulmonary Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

Correspondence Address:
Dr. Ram Nawal Rao
Professor, Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226 014, Uttar Pradesh
India

Background: Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) allows precise real-time sampling of intrathoracic lesions and is a minimally invasive, safe, and cost effective technique with high diagnostic yield. The aim of the current study is to evaluate utility of EBUS-TBNA cytology with cellblocks (CBs) in the diagnosis and subtyping of the intrathoracic lesions. Materials and Methods: It was a prospective study conducted from October 2015 to October 2017. We received 233 cases of intrathoracic lesions for EBUS-TBNA, of which CB was made in 217 cases. A flexible endobronchial ultrasound scope was used to sample the lesions. Results: There were 89 females and 128 males amongst the total 217 patients (age range: 14–85 years, mean age: 48.35 years). The smears from EBUS-TBNA contained adequate material in 137/144 [95.1%] non-neoplastic cases and 34/36 [94.4%] of the neoplastic cases, whereas the CBs provided adequate material in 94/144 [65.3%] non-neoplastic cases and 37/40 [92.5%] neoplastic cases. The CB helped subtyping the malignancy in 19 cases and of these immunohistochemistry (IHC) was done on the CB in 15 cases. The biopsy was non-diagnostic in 17/36 cases of granulomatous pathology and 4/18 neoplastic cases diagnosed with EBUS-TBNA.3. Conclusions: EBUS-TBNA provides rapid diagnosis through cytology and the material recovered in the same setting for the CB preparation can be used for immunohistochemical analysis and it may at times provide the diagnosis in cases where the smears are non-diagnostic.


How to cite this article:
Verma V, Khan A, Rao RN, Nath A, Hashim Z. Role of Endobronchial ultrasound guided transbronchial needle aspiration with cellblocks in diagnosis and subtyping of intrathoracic lesions: Two year experience from a tertiary care center.J Cytol 2021;38:120-126


How to cite this URL:
Verma V, Khan A, Rao RN, Nath A, Hashim Z. Role of Endobronchial ultrasound guided transbronchial needle aspiration with cellblocks in diagnosis and subtyping of intrathoracic lesions: Two year experience from a tertiary care center. J Cytol [serial online] 2021 [cited 2022 Aug 13 ];38:120-126
Available from: https://www.jcytol.org/article.asp?issn=0970-9371;year=2021;volume=38;issue=3;spage=120;epage=126;aulast=Verma;type=0