Journal of Cytology

SYMPOSIUM
Year
: 2019  |  Volume : 36  |  Issue : 2  |  Page : 118--123

Core needle biopsy versus fine needle aspiration cytology in bone and soft tissue tumors


Bharat Rekhi 
 Department of Surgical Pathology, Tata Memorial Centre, Parel, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Bharat Rekhi
Room Number 818, Department of Surgical Pathology, 8th Floor, Annex Building, Tata Memorial Hospital, Dr E.B. Road, Parel, Mumbai - 400 012, Maharashtra
India

Fine needle aspiration cytology (FNAC) for diagnosis of musculoskeletal tumors is well discussed and debated. The current evidence restricts its application in recurrent and metastatic lesions, with core needle biopsy as the acceptable technique/gold standard for the primary diagnosis of these challenging tumors. However, there are several studies showing reasonable sensitivity and specificity in primary diagnosis of bone and soft tissue tumors, especially in differentiating benign from malignant tumors. There is an acceptable limitation in the exact subtyping of soft tissue tumors, based on cytology smear examination, in the absence of ancillary techniques. Nonetheless, cytology constitutes an optimal material for triaging cases for ancillary techniques, such as immunocytochemistry, immunohistochemistry, molecular cytogenetics, and molecular diagnosis, in the form of smears and cell block preparations. This review focuses on the strengths and limitations of cytology versus core needle biopsy in the diagnosis of bone and soft tissue tumors, with the current evidence in the form of published studies, including the authors' experience.


How to cite this article:
Rekhi B. Core needle biopsy versus fine needle aspiration cytology in bone and soft tissue tumors.J Cytol 2019;36:118-123


How to cite this URL:
Rekhi B. Core needle biopsy versus fine needle aspiration cytology in bone and soft tissue tumors. J Cytol [serial online] 2019 [cited 2022 May 18 ];36:118-123
Available from: https://www.jcytol.org/article.asp?issn=0970-9371;year=2019;volume=36;issue=2;spage=118;epage=123;aulast=Rekhi;type=0