Journal of Cytology
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Year : 2011  |  Volume : 28  |  Issue : 1  |  Page : 36-38

Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant

1 Department of Pathology and Neurology, Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India
2 Department of Pathology and Obstretics and Gynaecology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, India

Correspondence Address:
Anshu Gupta
1408/13, Opp. Model School, Civil Road, Rohtak - 124 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-9371.76949

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Virus associated hemophagocytic syndrome is a non-neoplastic, generalized histiocytic proliferation with prominent hemophagocytosis associated with a systemic viral infection. We report a case of cytomegalovirus (CMV) associated hemophagocytic syndrome in a 2 month old male child presenting with rashes, fever, hepatosplenomegaly, cervical lymphadenopathy and pancytopenia. Fine needle aspiration cytology and biopsy from cervical lymph nodes revealed prominent hemophagocytosis. Serology for CMV IgM was positive in both the mother and the child, suggesting recent infection. Possibly there was intrauterine transmission of the infection.

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