Journal of Cytology
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Year : 2008  |  Volume : 25  |  Issue : 1  |  Page : 13-17

Role of fine needle aspiration cytology in diagnosis and ­management of thyroid lesions: A study on 434 patients

1 Department of Pathology, Government Medical College and Hospital, Chandigarh, India
2 Department of ENT and Head and Neck Surgery, Government Medical College and Hospital, Chandigarh, India

Correspondence Address:
Sukant Garg
Department of Pathology, Govt. Medical College, Sector-32A, Chandigarh - 160 047
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-9371.40652

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Objectives: To evaluate the results of fine needle aspiration cytology (FNAC) in the diagnosis and management of thyroid lesions. Materials and Methods: A review was conducted of FNAC of diffuse or nodular thyroid lesions performed on 434 patients over a period of three years. The cytological results were correlated with clinical features, biochemical investigations, and subsequent histopathological examination and management of the patients. Results: The most frequently encountered lesion was the colloid goiter in 250 (57.60%) cases followed by thyroiditis in 119 (27.41%) cases, ten (2.30%) adenomatous goiters and two (0.004%) thyroglossal cysts. In the neoplastic group, 14 (1.38%) cases were reported as follicular/Hurthle cell neoplasms and 17 (3.91%) as malignant tumors. When compared with the clinical diagnosis, FNAC proved to be an improvement on the diagnosis of thyroiditis and malignancy when compared with that of goiter. FNA revealed a sensitivity of 97%, a specificity of 100%, a positive predictive value of 96% and a negative predictive value of 100%. Conclusions: FNAC is a minimally invasive, highly accurate and cost-effective procedure for the assessment of patients with thyroid lesions. It also helps in differentiating lesions that require surgery from those that can be managed otherwise.

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