| ORIGINAL ARTICLE |
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| Year : 2008 | Volume
: 25
| Issue : 1 | Page : 13-17 |
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Role of fine needle aspiration cytology in diagnosis and management of thyroid lesions: A study on 434 patients
Uma Handa1, Sukant Garg1, Harsh Mohan1, Nitin Nagarkar2
1 Department of Pathology, Government Medical College and Hospital, Chandigarh, India
2 Department of ENT and Head and Neck Surgery, Government Medical College and Hospital, Chandigarh, India
Correspondence Address:
Sukant Garg
Department of Pathology, Govt. Medical College, Sector-32A, Chandigarh - 160 047
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0970-9371.40652
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Objectives: To evaluate the results of fine needle aspiration cytology (FNAC) in the diagnosis and management of thyroid lesions.
Materials and Methods: A review was conducted of FNAC of diffuse or nodular thyroid lesions performed on 434 patients over a period of three years. The cytological results were correlated with clinical features, biochemical investigations, and subsequent histopathological examination and management of the patients.
Results: The most frequently encountered lesion was the colloid goiter in 250 (57.60%) cases followed by thyroiditis in 119 (27.41%) cases, ten (2.30%) adenomatous goiters and two (0.004%) thyroglossal cysts. In the neoplastic group, 14 (1.38%) cases were reported as follicular/Hurthle cell neoplasms and 17 (3.91%) as malignant tumors. When compared with the clinical diagnosis, FNAC proved to be an improvement on the diagnosis of thyroiditis and malignancy when compared with that of goiter. FNA revealed a sensitivity of 97%, a specificity of 100%, a positive predictive value of 96% and a negative predictive value of 100%.
Conclusions: FNAC is a minimally invasive, highly accurate and cost-effective procedure for the assessment of patients with thyroid lesions. It also helps in differentiating lesions that require surgery from those that can be managed otherwise. |
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