Journal of Cytology
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Year : 2001  |  Volume : 18  |  Issue : 2  |  Page : 99-104

Vasoformative tumours - Cytomorphology and diagnostic pitfails

1 Associate Professor, Cytopathology Unit, Pathology Department, MAMC & LN Hospital, New Delhi -110 002, India
2 Professor, Cytopathology Unit, Pathology Department, MAMC & LN Hospital, New Delhi -110 002, India

Correspondence Address:
Neeta Kumar
178, Haus Khas Apartments (SF5), New Delhi 110 016
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Source of Support: None, Conflict of Interest: None

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Ten cases suspected to be vasoformative tumours on aspiration cytology were reviewed and correlated with histology. Patients presented with no specific clinical features including age, sex and site. Giemsa stained smears were hypercellularin all the cases. Loose cohesive clusters of round to oval cells, prominent branching vascular channels and pink stromal material were the predominant cytological features. Features suggestive of angiogenesis i.e., tumour cells in parallel rows on stromal scaffold, double rows of highly atypical spindle cells branching out in various directions and atypical endothelial cells were present in smears from three cases histologically confirmed as angiosarcoma. Two cases diagnosed as vasoformative tumour on cytology were metastatic renal cell carcinoma and skin adnexal tumor on histology. Tumours mimicking vasoformative pattern will remain a diagnostic pitfall. The preliminary information on the nature of the lesion helps in judicious selection of antibody panel for confirmation.

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