Journal of Cytology
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Year : 2000  |  Volume : 17  |  Issue : 2  |  Page : 111-114

Charcot-Leyden crystals in amoebic liver abscess

1 Professor of Pathology, Cancer Hospital and Research, Gwalior, M.P, India
2 Assistant Professor of Surgery, Cancer Hospital and Research, Gwalior, M.P, India
3 Assistant Professor of Radiodiagnosis, Cancer Hospital and Research, Gwalior, M.P, India
4 Assistant Professor of Pathology, Cancer Hospital and Research, Gwalior, M.P, India

Correspondence Address:
D C Gupta
D-10, Chetakpuri, Jhansi Road, Gwalior 474009
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Source of Support: None, Conflict of Interest: None

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To establish the importance of Charcot-Leyden Crystals (CLC) as a goodcytologicalcriterion for amoebic liver abscess, fine needle aspiration cytology (FNAC) smears of eleven cases of liver abscesses positive for CLC, were studied. Cytological findings were co-related with clinical presentation, ultrasonographicfindings andtherapeutic response. In allelevencases presumptive diagnosis of amoebic liver abscess was made on the findings of CLC in FNAC smears. In one case amoebic tropozoites were also seen. Five cases (out of eleven) received antiamoebic therapy. Four of these cases were followed on the basis of serial ultrasound and one was followed on the basis of clinical findings. All these five cases recovered completely. Six remaining cases were lost follow-up. Since amoebic trophozoites are not so commonly found in amoebic liver abscess, presence of CLC in FNAC smears of liver abscess is a good cytological finding. This finding assumes more significance in regions where amoebic liver abscess is quite common and all the patients do not have access to expensive ELISA (Enzyme Linked Immunosorbent Assay) tests. Since CLC are well appreciated in wet films, it can be used as a simple and cheap screening procedure in busy outpatients department of a hospital.

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