Journal of Cytology
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Year : 1998  |  Volume : 15  |  Issue : 2  |  Page : 29-32

Fine needle aspiration cytology of breast: Analysis of audit data

1 Assiciate Professor, Dept. of Pathology, Indira Gandhi Medical College, Nagpur, India
2 (Ex)Professor and Head, Dept. of Pathology, Indira Gandhi Medical College, Nagpur, India
3 Lecturer, Dept. of Pathology, Indira Gandhi Medical College, Nagpur, India

Correspondence Address:
M M Kamal
MIG Colony, MA-8, Laxmi Nagar, Nagpur-440 022. M.S
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Source of Support: None, Conflict of Interest: None

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Quality assurance in the form of evaluating rates of correct diagnosis and errors is essential for any cytology laboratory rendering define cytological diagnosis. This audit was performed to assess the accuracy of aspiration cytology for preoperative diagnosis of cancer of the breast and detect the reasons for histology/cytology discrepancies. FNAC was performed on 705 patients presenting with palpable breast lumps. Tissue for correlation was available for 221 (31.34%) cases. These included 15 cases in whom cytologic material was insufficient for diagnosis. The final statistical analysis is based on 206 cases in whom cytologic diagnosis was given. 0f the 206 cases, 136 were benign and 70 were malignant on histology. The rate of false negative diagnosis was 4.28%, and false positive was 2.2%. No mastectomies were performed for benign disease. The sensitivity of the procedure was 95.71%, specificity and efficiency of the test was 87.08%. The positive and negative predictive values were 95.71% and97.79% respectively. The likehood ratios (LR) for a positive and negative test were43.39and0.044 respectively. Our results indicate that cytology can detect benign and malignant breast disease with high accuracy: The use of aspiration cytology to exclude malignancy is more difficult. Reasons for histology/cytology discrepancies are multifactorial. The test statistics described in this study could be used as guidelines and standards for judging whether a cytology department has gained sufficient competence and skill in diagnosing breast lesions by FNA.

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