Journal of Cytology
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ORIGINAL ARTICLE
Year : 1998  |  Volume : 15  |  Issue : 2  |  Page : 17-22

Fine needle aspiration cytology of salivary gland lesions - A reappraisal

Radha R Pai1, CV Raghuveer2, Kausalya Sahu3, Shankari Shenoy4
1 Additional Professor, Department of Pathology, Kasturba Medical College, Mangalore, Karnataka, India
2 Professor, Department of Pathology, Kasturba Medical College, Mangalore, Karnataka, India
3 Associate Professor, Department of Pathology, Kasturba Medical College, Mangalore, Karnataka, India
4 Tutor, Department of Pathology, Kasturba Medical College, Mangalore, Karnataka, India

Correspondence Address:
Radha R Pai
Department of Pathology, Kasturba Medical College, P.O.Box 53, Mangalore - 575 001. Karnataka
India
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Source of Support: None, Conflict of Interest: None


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The aim of the study was to review the cytodiagnosis of salivary gland lesions. From January 1990 to December 1996 among 150 patients with salivary gland enlargement referred for FNAC 106 aspirates were from the parotid gland (70.7%), 41 from submandibular gland (27.3%) and 3 (2%) from minor salivary glands of the palate. Fortysix (30.6%) aspirates were diagnosed as non-neoplastic lesions and 64 (42.7%) as benign neoplasms. Among the 40 malignant tumours 32 (21.3%) were primary, 4 (2.7%) were metastatic carcinoma, one was Hodgkin's disease (0.7%) and in 3 cases (2%) differential diagnoses were considered. Based on histologic correlation in only 53 cases (48.2%) the sensitivity of the test for malignancy was 79.4% (false negative rate 20.8%) and specificity 100%. Misinterpretation of the background stroma was responsible for low sensitivity in this study. The cytopathologist should be acquainted with the variety of background stromal material seen in different salivary gland lesions and correlate it with subtle cytomorphologic features to avoid major diagnostic errors.


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Online since 15th April, 2008