Journal of Cytology
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Year : 1997  |  Volume : 14  |  Issue : 2  |  Page : 47-54

Morphometric description of chromatin pattern in breast carcinoma

1 Associate Professor, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Lecturer of Statistics, Punjab University, Chandigarh, India

Correspondence Address:
Raje Nijhawan
Associate Professor of Cytology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
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Source of Support: None, Conflict of Interest: None

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The chromatin texture of nuclei from breast carcinoms were described by image morphometry in this pilot study on nine FNA samples. The series included three patients each of Grades I, II and III. The parameters employed were; Skewness Index, Kurtosis Index, Variance of Optical Density, Coefficient of variation, Run Number, and Uniformity of Run Length. The data obtained more or less reflected the visual impressions regarding the chromatin texture of the nuclei studied. Larger studies are recommended in order to assess whether morphometric description of chromatin can complement the existing grading systems.

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