Journal of Cytology
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Year : 1997  |  Volume : 14  |  Issue : 1  |  Page : 21-24

Detection of helicobacter pylori in gastric brush smears - A clinicocytological correlation

1 Department of Pathology, Maulana Azad Medical College & Associated Hospital, New Delhi-110 002, India
2 Department of Medicine, Maulana Azad Medical College & Associated Hospital New Delhi-110 002, India

Correspondence Address:
Shyama Jain
20/59 Lodhi Colony, New Delhi -110 003
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Source of Support: None, Conflict of Interest: None

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Twenty five patients presenting with dyspepsia over a period of two months were subjected to endoscopy. Brush smears were stained with Giemsa and Half-Gram stain and compared. Endoscopic gross lesions were correlated with presence and density of Hpylori and associated cellular changes in gastric brush smears. Overall H. pylori positivity was 60% in our study. The bacilli were seen in cases of duodenal ulcer (100%), gastric ulcer (80%), antral erosion with gastritis (100%) and antral gastritis (55.5%). 70% of H. pylori positive cases had acute and chronic inflammation, remaining had only chronic inflammation. 5 cases showed focal mild dysplasia of which 4 were H.pylori positive. 5 out of 9 cases of antral gastritis had moderate inflammation irrespective of density of H. pylori. Highest prevalence of H.pylori positivity was seen in fifth decade with decline thereafter. Thus endoscopic brush cytology is useful in detection of H.pylori and associated cellular changes.

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