Journal of Cytology
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Year : 1996  |  Volume : 13  |  Issue : 1  |  Page : 11-13

Comparison of AgNOR counts in fine needle aspirates and tissue sections of breast neoplasms

1 Department of Pathology, K.G. Medicai College, Lucknow - 226 003, India
2 Department of Clinical Epidemiology, K.G. Medicai College, Lucknow - 226 003, India

Correspondence Address:
Amitabh Srivastava
Dept. of Pathology, University College of Medical Sciences, New Delhi - 110095
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Source of Support: None, Conflict of Interest: None

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Silver staining to demonstrate nucleolar organizer regions (NORs) was performed on fine needle aspiration (FNA) smears from 31 cases with palpable breast lumps. Correlation with histology was done in all cases. Staining in FNA smears was found superior than in tissue sections. Enumeration of AgNORs revealed a broad zone of overlap between benign and malignant breast lesions. The counts in FNA smears when compared to those in tissue sections of the same lesion were not always found to be representative of the main tumour mass. The method therefore is of little use when applied to FNA smears. It may however, be of some relevance when applied to histopathological sections in specific instances.

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