Journal of Cytology
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Year : 1995  |  Volume : 12  |  Issue : 1  |  Page : 9-13

Immunocytochemistry of malignant effusions

Tissue Path, M-l, Raja House, Nehru Place, New Delhi - 110 019, India

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Immunocytochemistry analysis was carried out on 5 effusion fluids using Cytokeratin, Epithelial membrane antigen, Carcinoembryonic antigen and Vimentin. Cytokeratin was positive in all the cases including one case of mesothelioma. Epithelial membrane antigen staining was cytoplasmic in carcinomas but showed thick membranous staining with spiky projections in the case of mesothelioma. Carcinoembryonic antigen was negative in mesothelioma and prostatic carcinoma. Vimentin did not help in distinguishing carcinoma from mesothelioma.

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